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Balancing Ultrastructural Synaptic Plasticity During Changes in Synapse Function
(VTC)
Kristen Harris, PhD
Professor of Neurobiology, Center for Learning and Memory, Institute of Neuroscience, University of Texas
A seminar in the Research Institute Seminar Series
Kristen Harris, PhD, conducts research using 3D reconstructions from electron microscopy to decode the cell biology of learning and memory. Recent findings show that mature neurons sustain a maximum synaptic capacity, exactly balancing the strengthening of some synapses by eliminating weak neighbors during long-term potentiation, a cellular mechanism of learning. These novel findings provide the basis for new understanding of structural and molecular mechanisms of synapse growth and elimination in the mature brain, a crucial step in developing treatments to mend the mind.
Live Webcast: http://research.vtc.vt.edu/live-webcast
Hosted by: Michael J. Friedlander, PhD, Executive Director, Virginia Tech Carilion Research Institute
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540-526-2013