NOTICE: As of September 18, 2023, login to calendar.vt.edu was disabled. Calendar admins will no longer be able to add new events or modify existing events.
If you need assistance with an existing event on calendar, please contact us: https://webapps.es.vt.edu/support/.

 Event Calendar
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
   Day      Week     Month  
1 1 1 1 1
 
1 1 1 1 1 1 1 1 1 1 1 1
   Search      Update  
1 1 1


Thursday, March 29, 2007
 

Mar 2024
  S M T W T F S
W08 25 26 27 28 29 1 2
W09 3 4 5 6 7 8 9
W10 10 11 12 13 14 15 16
W11 17 18 19 20 21 22 23
W12 24 25 26 27 28 29 30
W13 31 1 2 3 4 5 6


Today is:
Sat, Mar 2, 2024


Subscribe & download

Filter events


4:00pm
to
5:00pm
  Genetics, Bioinformatics & Computational Biology (GBCB) Seminar  
(Seminar/Conference)

Speaker: Dr. Ron Breaker, Yale University, Professor in the Department of Molecular, Cellular & Developmental Biology

Title: Discovering Genetic Switches and Logic Gates Made of RNA

Abstract: Riboswitches are natural metabolite-binding RNAs that control gene expression in many bacterial species. They typically are found in the non-coding regions of certain messenger RNAs, and control gene expression by ligand-induced allosteric changes in RNA structure. The most highly conserved portion of riboswitches is the
metabolite-binding aptamer domain, whose sequence and structural features define each riboswitch class. Of the proven riboswitch classes, the shortest aptamer domain measures only 34 nucleotides while the largest requires approximately 200 nucleotides. Interestingly, even the smaller riboswitch domains appear to be capable of functioning as complex genetic switches. For example, we have identified a riboswitch that uses twligand-binding domains to bind two glycine molecules. Together, these domains cooperate to function as a more “digital” genetic switch, thus allowing the organism to control gene expression in response to small changes in the concentration of glycine. More recently, we have identified natural RNAs that use components of different riboswitch classes to function like two-input Boolean logic gates. Our findings support the view that RNA is a versatile medium for the construction of complex genetic elements.

Public welcome, please come! Refreshments 3:15-3:50 pm,
seminar starts promptly at 4pm.



More information...


Location: VBI Auditorium
Price: FREE
Contact: Dennie Munson
E-Mail: dennie@vt.edu
540-231-1928
   
copy this event into your personal desktop calendar
powered by VTCalendar 2.2.1