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Parallel Universes: G's and A's in Autoimmunity
(VTC)
Robert Kimberly, MD
Howard L. Holley Professor of Medicine
Senior Associate Dean for Research
Director of the Comprehensive Arthritis
Musculoskeletal and Autoimmunity Center
University of Alabama at Birmingham School of Medicine
Autoimmune diseases--which are often chronic, debilitating, and life-threatening--affect millions of people in the United States alone. Robert Kimberly, MD, will explain the role that two types of autoimmune molecules, IgG and IgA autoantibodies, play in these diseases. He will also describe the importance of biologically significant, genetically determined differences in shaping the response to these antibodies. In the autoimmune disorder Wegener's granulomatosis, for example, the combination of IgA autoantibody and specific receptor variants is strongly associated with kidney damage. This relationship sets the paradigm for the coming together of the sciences of genomics and proteomics for predictive personalized medicine.
Robert Kimberly, MD, is the Howard L. Holley Professor of Medicine at the University of Alabama, Birmingham, where he is also the senior associate dean for research and director of the UAB Comprehensive Arthritis, Musculoskeletal and Autoimmunity Center. A rheumatologist and immunologist, Dr. Kimberly conducts research aimed at understanding the role of genetic factors in the normal function of the immune system and in the development of immunological diseases such as systemic lupus erythematosus, systemic vasculitis, and rheumatoid arthritis.
This lecture is part of the Distinguished Visiting Scholars Series.
Webcast: http://research.vtc.vt.edu/live-webcast/
Hosted by: Michael J. Friedlander, PhD, Executive Director, VTCRI
A public reception will precede this event in the VTC Cafe at 4:30 p.m.
More information...
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540-526-2013