1:00pm
to
2:00pm |
|
Imaging Intact Cells in 3-D in Near-Native States to Macromolecular Resolution: Case Studies and Future Prospects
(VTC)
Grant Jensen, PhD
Professor of Biology
California Institute of Technology
Pasadena, California
Grant Jensen, PhD, will discuss the contributions, limitations, and future prospects of electron cryotomography using specific biological case studies, including the bacterial actin-homolog MreB, chemoreceptor arrays, sporulation, and the HIV life cycle.
Grant Jensen, PhD, earned his doctorate in biophysics at Stanford University before undertaking a postdoctoral fellowship at the Lawrence Berkeley National Laboratory. In 2002, he joined the faculty of the California Institute of Technology, where he is now an associate professor of biology. He has been a Howard Hughes Medical Institute investigator since 2008. His laboratory uses state-of-the-art electron cryomicroscopy techniques to understand the structure and function of large protein machines and their arrangement within cells. His projects range from theoretical studies on the mathematics of three-dimensional reconstructions to direct imaging of individual protein complexes to tomography of viruses and cells. He hopes eventually to combine these results with the vast data emerging from genomics, proteomics, and structural genomics to enable authentic, whole-cell simulations that allow the rational design of entirely new species for the production of clean fuels, water desalination, bioremediation, and medical applications.
This lecture is part of the Distinguished Visiting Scholars Series.
Webcast: http://research.vtc.vt.edu/live-webcast/
Hosted by: Michael J. Friedlander, PhD, Executive Director, VTCRI
More information...
|
540-526-2013