The Interplay Between T-bet and Bcl-6 in T Helper Cell Differentiation
Kenneth J. Oestreich, PhD
Senior Postdoctoral Fellow
Weinmann Laboratory, Department of Immunology
University of Washington, Seattle, Washington
T helper cells are critical to coordinate the immune response. Specialized T helper cell populations arise from a common naive CD4+ T cell progenitor and this is dependent upon a group of lineage-specifying transcription factors. In this talk, Dr. Oestreich will discuss how the interaction between two such factors, T-bet and Bcl-6, regulates flexibility between T helper cell phenotypes.
Live Webcast: http://research.vtc.vt.edu/live-webcast
Hosted by: Michael J. Friedlander, PhD, Executive Director, Virginia Tech Carilion Research Institute