NanoEarth Industry Speaker: Predictive toxicological modeling: applications for fibrous minerals, lessons for nanoparticles
Speaker: Andrey Korchevskiy, PhD, CIH, Chemistry & Industrial Hygiene, Inc. (Denver, Colorado)
Host: Matthew Hull, Associate Director, Innovation & Entrepreneurship, NanoEarth
Title: Predictive toxicological modeling: applications for fibrous minerals, lessons for nanoparticles
Fibrous minerals are again in the focus of toxicological and epidemiological studies. Naturally Occurring Asbestos (NOA) and similar agents (like "the most toxic mineral on the Earth," erionite) require risk assessment in many situations relevant for public health protection and occupational regulations. However, and very often, there is no sufficient information for emerging toxicants, to evaluate cancer potency and the shape of dose-response curve. Dr. Korchevskiy will demonstrate one of the possible approaches for predictive toxicological modeling, based on the chemical composition and structural characteristics of the fibers. The presenter will discuss implications, uncertainties and limitations of this types of models, along with possible lessons for nanotoxicology and other related areas. The role of a collaboration between government, industry and academia in risk assessment for emerging hazards (like, erionite, or nanotubes) will also be discussed.
Dr. Andrey Korchevskiy is a Director of Research and Development in C&IH (Wheat Ridge, Colorado). He is one of the leading specialists in risk assessment modeling for industrial hygiene and environmental health applications. He arranged and taught risk assessment classes in the US, UK, Canada, Mexico, Colombia, and Ukraine, and has over 150 scientific publications in the fields of industrial hygiene, epidemiology, toxicology, and biostatistics.